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pentobarbital will reduce the level or outcome of nitrendipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.pentobarbital will decrease the level or impact of norgestrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Moderate CYP3A4 inducers may well reduce progestin